Journal article icon

Journal article

Highly stable single-strand-specific 3′-nuclease/nucleotidase from Legionella pneumophila

Abstract:

The Gram-negative bacterium Legionella pneumophila is one of the known opportunistic human pathogens with a gene coding for a zinc-dependent S1–P1 type nuclease. Bacterial zinc-dependent 3′-nucleases/nucleotidases are little characterized and not fully understood, including L. pneumophila nuclease 1 (Lpn1), in contrast to many eukaryotic representatives with in-depth studies available. To help explain the principle properties and role of these enzymes in intracellular prokaryotic pathogens we...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1016/j.ijbiomac.2018.03.113

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Biology
Role:
Author
ORCID:
0000-0002-3705-2993
More from this funder
Grant:
CZ.1.05/2.1.00/19.0390, CZ.02.1.01/0.0/0.0/16_013/0001776
Publisher:
Elsevier Publisher's website
Journal:
International Journal of Biological Macromolecules Journal website
Volume:
114
Pages:
776-787
Publication date:
2018-03-23
Acceptance date:
2018-03-21
DOI:
ISSN:
0141-8130
Keywords:
Pubs id:
pubs:868514
UUID:
uuid:6cd2bb34-bc15-410d-84f7-c2997d1fe00a
Local pid:
pubs:868514
Source identifiers:
868514
Deposit date:
2018-07-13

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP