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Two loci on chromosomes 2 and X for premature coronary heart disease identified in early- and late-settlement populations of Finland.

Abstract:

Coronary heart disease (CHD) is a complex disorder constituting a major health problem in Western societies. To assess the genetic background of CHD, we performed a genomewide linkage scan in two study samples from the genetically isolated population of Finland. An initial study sample consisted of family material from the northeastern part of Finland, settled by a small number of founders approximately 300 years ago. A second study sample originated from the southwestern region of Finland, s...

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Publisher copy:
10.1086/316902

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Journal:
American journal of human genetics
Volume:
67
Issue:
6
Pages:
1481-1493
Publication date:
2000-12-01
DOI:
EISSN:
1537-6605
ISSN:
0002-9297
Source identifiers:
366044
Language:
English
Keywords:
Pubs id:
pubs:366044
UUID:
uuid:6cce7e56-84ae-4353-90e4-79466eec0ca1
Local pid:
pubs:366044
Deposit date:
2013-11-16

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