Journal article
The expression and regulation of ADAMTS-1, -4, -5, -9, and -15, and TIMP-3 by TGFbeta1 in prostate cells: relevance to the accumulation of versican.
- Abstract:
-
BACKGROUND: Benign prostatic hyperplasia (BPH) is characterized by a proportional increase in the size of the stromal compartment of the gland, involving alterations to extracellular matrix (ECM) components. Some of these changes have been associated with the activity and expression of transforming growth factor beta1 (TGFbeta1). Versican (chondroitin sulphate proteoglycan-2) is overexpressed in BPH and prostate cancer and potentially contributes to disease pathology. A sub-group of the ADAM...
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- Publication status:
- Published
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- Publisher copy:
- 10.1002/pros.20182
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Bibliographic Details
- Journal:
- Prostate
- Volume:
- 63
- Issue:
- 3
- Pages:
- 269-275
- Publication date:
- 2005-05-01
- DOI:
- EISSN:
-
1097-0045
- ISSN:
-
0270-4137
- Source identifiers:
-
120728
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:120728
- UUID:
-
uuid:6ccde647-59c7-459a-ac4b-be32d9d2b4a5
- Local pid:
- pubs:120728
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2005
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