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Journal article

SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development

Abstract:

Arterial specification and differentiation are influenced by a number of regulatory pathways, encompassing numerous growth factors, signaling molecules and transcription factors. While it is known that the Vegfa-Notch cascade plays a central role in this biological process, the transcriptional hierarchy controlling arterial specification has not been fully delineated. To elucidate the direct transcriptional regulators of Notch receptor expression in arterial endothelial cells, we used histone...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1242/dev.146241

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Oxford Ludwig Institute
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Oxford Ludwig Institute
Role:
Author
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Ludwig Cancer Research More from this funder
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Publisher:
Company of Biologists Publisher's website
Journal:
Development Journal website
Volume:
144
Issue:
14
Pages:
2629-2639
Publication date:
2017-06-15
Acceptance date:
2017-06-07
DOI:
EISSN:
1477-9129
ISSN:
0950-1991
Source identifiers:
698722
Keywords:
Pubs id:
pubs:698722
UUID:
uuid:6ccbd1aa-72e4-4529-906c-0b7227254a27
Local pid:
pubs:698722
Deposit date:
2017-06-08

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