Journal article
Ethyl 2-(2,3-dihyroxybenzamido) ccetate induces hypoxia induced factor-related metabolic changes in cardiosphere-derived cells for myocardial infarction therapy
- Abstract:
-
Hypoxia induced factor (HIF) transcriptional complex is a potent inducer of cytokines that enhances therapeutic potential of stem cell. Here, ethyl 2-(2,3-dihyroxybenzamido) acetate (EDBA) was used to stabilize HIF-α in cardiosphere-derived cells (CDCs) with the aim of enhancing their therapeutic potential for myocardial infarction. In this study, neonatal Sprague Dawley (SD) rat hearts (n=12) were excised, minced and cultured to generate explant-derived...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Malaysian Ministry of Higher Education
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Bibliographic Details
- Publisher:
- Universiti Sains Malaysia Publisher's website
- Journal:
- Health and the Environment Journal Journal website
- Volume:
- 7
- Issue:
- 2
- Pages:
- 77-95
- Publication date:
- 2016-11-01
- Acceptance date:
- 2016-11-21
- ISSN:
-
2180-1126
- Source identifiers:
-
664353
Item Description
- Keywords:
- Pubs id:
-
pubs:664353
- UUID:
-
uuid:6cb6b24a-5d5a-49b8-9f2f-54dcd095b0a9
- Local pid:
- pubs:664353
- Deposit date:
- 2016-12-07
Terms of use
- Copyright holder:
- Universiti Sains Malaysia
- Copyright date:
- 2016
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