Clinical, immunological, and pathological aspects of operational tolerance after pediatric living-donor liver transplantation.

Conference item

In the setting of our pediatric living-donor liver transplantation (LDLT), 87 patients (15.0% of all the patients: significantly higher proportion, compared with those of other transplant centers) achieved complete withdrawal of immunosuppression, which is referred to as "operational tolerance". Immunosuppressants were completely discontinued for 54 patients as scheduled, and for 33 because of EBV infection or other complications. Immunological analyses of the peripheral blood derived from op...

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Authors: Koshiba, T; Li, Y; Takemura, M; Wu, Y; Sakaguchi, S

• Publication status: Published
• Host title: Transplant immunology
• Volume: 17
• Issue: 2
• Pages: 94-97
• Publication date: 2007-02-01
• Event location: England
• DOI: 10.1016/j.trim.2006.10.004
• EISSN: 1878-5492
• ISSN: 0966-3274
• Keywords: Child; Adolescent; Immunosuppression; Biopsy; Liver; Fetus; Female; Male; Liver Transplantation; Forkhead Transcription Factors; Withholding Treatment; Receptors, Antigen, T-Cell, gamma-delta; Graft Rejection; Transplantation Tolerance; Child, Preschool; T-Lymphocytes, Regulatory; Living Donors; Humans