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Cortical glutathione levels in young people with bipolar disorder: a pilot study using magnetic resonance spectroscopy.

Abstract:

RATIONALE: Glutathione (GSH) is a key scavenger for cellular free radicals, and patients with bipolar disorder may have lowered GSH levels in plasma and in post-mortem brain tissue. OBJECTIVES: The objective of the current study was to use magnetic resonance spectroscopy (MRS) to measure cortical GSH levels in young people with bipolar disorder to determine if lowered GSH might be a useful biomarker of vulnerability to the illness. METHODS: We studied 13 patients with DSM-IV bipolar disorder ...

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Publication status:
Published

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Publisher copy:
10.1007/s00213-013-3244-0

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
Journal:
Psychopharmacology
Volume:
231
Issue:
2
Pages:
327-332
Publication date:
2014-01-05
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
URN:
uuid:6cb505af-0c57-4bb8-8dd9-17e3f546bd3c
Source identifiers:
418376
Local pid:
pubs:418376

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