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Journal article

Complete controllability analysis of the Wnt signalling pathway

Abstract:

In the face of the ever increasing knowledge of biochemical interactions, understanding the functionality of complex biochemical systems and how to control them is becoming a relevant and promising endeavour. Investigations of controllability of biochemical networks for biomedical applications has, with few exceptions, been limited to determining structural controllability. Using the Schmitz model for the Wnt signalling pathway as an example, we demonstrate how to perform complete controllab...

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Publication status:
Accepted
Peer review status:
Peer reviewed

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Department:
Oxford University
Publisher:
PLOS Publisher's website
Acceptance date:
2015-02-07
Language:
English

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