Journal article
Lack of repeat transduction by recombinant adeno-associated virus type 5/5 vectors in the mouse airway.
- Abstract:
-
While recombinant adeno-associated virus (rAAV) vectors promote long-term transgene expression in the lungs and other organs, the goal of correcting chronic inherited lung diseases such as cystic fibrosis with this type of viral gene transfer vector is limited by the requirement of achieving stable potent transgene expression, potentially requiring vector readministration. Here we evaluated the abilities of rAAV type 5/5 (rAAV5/5) vectors based on the genome and capsid of AAV5 to efficiently ...
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- Publisher copy:
- 10.1128/jvi.01010-07
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Authors
Bibliographic Details
- Journal:
- Journal of virology
- Volume:
- 81
- Issue:
- 22
- Pages:
- 12360-12367
- Publication date:
- 2007-11-01
- DOI:
- EISSN:
-
1098-5514
- ISSN:
-
0022-538X
- Source identifiers:
-
246477
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:246477
- UUID:
-
uuid:6c751d1f-e7cf-40c1-a95e-4d388f7d678e
- Local pid:
- pubs:246477
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2007
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