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Journal article

Challenges and progress in the development of a serogroup B meningococcal vaccine.

Abstract:

Serogroup B meningococci cause the majority of the meningococcal disease burden in developed countries. Production of an effective and safe vaccine for serogroup B organisms has been hampered by the poor immunogenicity of the capsular polysaccharide that defines this group of bacteria. Previous efforts have focused on outer membrane vesicle vaccines, which have been implemented successfully during clonal outbreaks. However, the search for a universal vaccine against endemic polyclonal serogro...

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Publication status:
Published

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Publisher copy:
10.1586/erv.09.30

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
Journal:
Expert review of vaccines More from this journal
Volume:
8
Issue:
6
Pages:
729-745
Publication date:
2009-06-01
DOI:
EISSN:
1744-8395
ISSN:
1476-0584
Language:
English
Keywords:
Pubs id:
pubs:119054
UUID:
uuid:6c6f9f58-8ae7-4c8f-a0c9-1127d0d74027
Local pid:
pubs:119054
Source identifiers:
119054
Deposit date:
2012-12-19

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