BACKGROUND AND AIMS: Genetic variation in the chromosome 5q31 cytokine cluster (IBD5 risk haplotype) has been associated with Crohn's disease (CD) in a Canadian population. We studied the IBD5 risk haplotype in both British and Japanese cohorts. Disease associations have also been reported for CARD15/NOD2 and TNF variants. Complex interactions between susceptibility loci have been shown in animal models, and we tested for potential gene-gene interactions between the three CD associated loci....Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease.
Views and Downloads
If you are the owner of this record, you can report an update to it here: Report update to this record