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Journal article

Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease.

Abstract:

BACKGROUND AND AIMS: Genetic variation in the chromosome 5q31 cytokine cluster (IBD5 risk haplotype) has been associated with Crohn's disease (CD) in a Canadian population. We studied the IBD5 risk haplotype in both British and Japanese cohorts. Disease associations have also been reported for CARD15/NOD2 and TNF variants. Complex interactions between susceptibility loci have been shown in animal models, and we tested for potential gene-gene interactions between the three CD associated loci....

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Publication status:
Published

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Publisher copy:
10.1136/gut.52.4.541

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Journal:
Gut
Volume:
52
Issue:
4
Pages:
541-546
Publication date:
2003-04-05
DOI:
EISSN:
1468-3288
ISSN:
0017-5749
URN:
uuid:6c6c8c5e-4c9e-40e6-93d9-d7e875c3ce3a
Source identifiers:
135333
Local pid:
pubs:135333

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