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Thesis

Incorporating inter-sample variability into cardiac electrophysiology simulations

Abstract:

Sudden cardiac death kills 5-10 people per 10,000 population in Europe and the US each year. Individual propensity to arrhythmia and sudden cardiac death is typically assessed through clinical biomarkers. Variability in these biomarkers is a major challenge for risk stratification. Variability is observed at a wide range of spatio-temporal scales within the heart, from temporal fluctuations in ion channel behaviour, to inter-cell and inter-regional differences in ion channel expression, to...

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Institution:
University of Oxford
Research group:
Computational Biology
Oxford college:
Balliol College
Department:
Mathematical,Physical & Life Sciences Division - Other - Systems Biology Doctoral Training Centre
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
URN:
uuid:6c653c3c-64e8-4337-bb97-728b99361573
Local pid:
ora:10215

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