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Mapping cardiac microstructure of rabbit heart in different mechanical states by high resolution diffusion tensor imaging: A proof-of-principle study

Abstract:

Myocardial microstructure and its macroscopic materialisation are fundamental to the function of the heart. Despite this importance, characterisation of cellular features at the organ level remains challenging, and a unifying description of the structure of the heart is still outstanding. Here, we optimised diffusion tensor imaging data to acquire high quality data in ex vivo rabbit hearts in slack and contractured states, approximating diastolic and systolic conditions. The data were analyse...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.pbiomolbio.2016.06.001

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, RDM Cardiovascular Medicine
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, RDM Cardiovascular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
Role:
Author
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Grant:
PG/13/33/30210, RE/13/1/30181, FS/11/50/29038, FS/12/17/29532
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Grant:
109371/Z/15/Z, 090532/Z/09/Z
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Grant:
Advanced Grant CardioNECT
Publisher:
Elsevier Publisher's website
Journal:
Progress in Biophysics and Molecular Biology Journal website
Publication date:
2016-06-16
DOI:
EISSN:
1873-1732
ISSN:
0079-6107
URN:
uuid:6c3a0721-6034-48ae-b9f0-7ced59a5095f
Source identifiers:
629432
Local pid:
pubs:629432

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