Journal article
A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium.
- Abstract:
-
BACKGROUND: Androgens are key regulators of prostate gland maintenance and prostate cancer growth, and androgen deprivation therapy has been the mainstay of treatment for advanced prostate cancer for many years. A long-standing hypothesis has been that inherited variation in the androgen receptor (AR) gene plays a role in prostate cancer initiation. However, studies to date have been inconclusive and often suffered from small sample sizes. OBJECTIVE AND METHODS: We investigated the associatio...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Journal of clinical endocrinology and metabolism
- Volume:
- 95
- Issue:
- 9
- Pages:
- E121-E127
- Publication date:
- 2010-09-01
- DOI:
- EISSN:
-
1945-7197
- ISSN:
-
0021-972X
- Source identifiers:
-
60453
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:60453
- UUID:
-
uuid:6c274746-35a0-4a34-955b-d526c22379bc
- Local pid:
- pubs:60453
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2010
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