- Abstract:
-
Artemisinin-resistant Plasmodium falciparum parasites are rapidly spreading in Southeast Asia, yet nothing is known about their transmission. This knowledge gap and the possibility that these parasites will spread to Africa endanger global efforts to eliminate malaria. Here we produce gametocytes from parasite clinical isolates that displayed artemisinin resistance in patients and in vitro, and use them to infect native and non-native mosquito vectors. We show that contemporary artemisinin-re...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 484.1kb)
-
- Publisher copy:
- 10.1038/ncomms9614
-
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- Grant:
- Intramural Research Program of the NIAID
- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- Nature communications Journal website
- Volume:
- 6
- Pages:
- 8614
- Publication date:
- 2015
- DOI:
- EISSN:
-
2041-1723
- ISSN:
-
2041-1723
- URN:
-
uuid:6c210f86-116b-42ef-a8ff-5e6723babf33
- Source identifiers:
-
572940
- Local pid:
- pubs:572940
- Language:
- English
- Copyright holder:
- St. Laurent et al.
- Copyright date:
- 2015
- Notes:
- This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Journal article
Artemisinin-resistant Plasmodium falciparum clinical isolates can infect diverse mosquito vectors of Southeast Asia and Africa.
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