Journal article
Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.
- Abstract:
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Observational epidemiological studies have shown that high body mass index (BMI) is associated with a reduced risk of breast cancer in premenopausal women but an increased risk in postmenopausal women. It is unclear whether this association is mediated through shared genetic or environmental factors.We applied Mendelian randomization to evaluate the association between BMI and risk of breast cancer occurrence using data from two large breast cancer consortia. We created a weighted BMI genetic...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 850.0KB)
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- Publisher copy:
- 10.1371/journal.pmed.1002105
Authors
Funding
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Medicine Journal website
- Issue:
- 8
- Publication date:
- 2016-08-23
- Acceptance date:
- 2016-06-24
- DOI:
- ISSN:
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1549-1277 and 1549-1676
- Pmid:
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27551723
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:640490
- UUID:
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uuid:6c16eb19-73da-4fb3-acb0-519402de4d1b
- Local pid:
- pubs:640490
- Source identifiers:
-
640490
- Deposit date:
- 2016-09-16
Terms of use
- Copyright holder:
- Guo et al
- Copyright date:
- 2016
- Notes:
- © 2016 Guo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License.
- Licence:
- CC Attribution (CC BY)
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