Journal article
Regulation of self-renewal and differentiation by the intestinal stem cell niche
- Abstract:
-
The gastrointestinal epithelium is a highly organised tissue that is constantly being renewed. In order to maintain homeostasis, the balance between intestinal stem cell (ISC) self-renewal and differentiation must be carefully regulated. In this review, we describe how the intestinal stem cell niche provides a unique environment to regulate self-renewal and differentiation of ISCs. It has traditionally been believed that the mesenchymal myofibroblasts play an important role in the crosstalk b...
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- Publisher copy:
- 10.1007/s00018-011-0687-5
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Bibliographic Details
- Journal:
- Cellular and Molecular Life Sciences
- Volume:
- 68
- Issue:
- 15
- Pages:
- 2513-2523
- Publication date:
- 2011-08-01
- DOI:
- EISSN:
-
1420-9071
- ISSN:
-
1420-682X
- Source identifiers:
-
304913
Item Description
- Pubs id:
-
pubs:304913
- UUID:
-
uuid:6c03a1f1-d2ea-428b-844d-6151021676a8
- Local pid:
- pubs:304913
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2011
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