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Journal article

Effect of temperature on the size distribution, shell properties, and stability of Definity®.

Abstract:

Physical characterization of an ultrasound contrast agent (UCA) aids in its safe and effective use in diagnostic and therapeutic applications. The goal of this study was to investigate the impact of temperature on the size distribution, shell properties, and stability of Definity®, a U.S. Food and Drug Administration-approved UCA used for left ventricular opacification. A Coulter counter was modified to enable particle size measurements at physiologic temperatures. The broadband acoustic atte...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
Acoustical Society of America More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Ultrasound in Medicine and Biology Journal website
Volume:
44
Issue:
2
Pages:
434-446
Publication date:
2017-11-22
Acceptance date:
2017-09-29
DOI:
EISSN:
1879-291X
ISSN:
0301-5629
Pubs id:
pubs:801118
URN:
uri:6bff0ae2-34d9-4a9a-88cd-84168e431ad5
UUID:
uuid:6bff0ae2-34d9-4a9a-88cd-84168e431ad5
Local pid:
pubs:801118

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