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Journal article

Sub-cellular targeting of constitutive NOS in health and disease.

Abstract:

Constitutive nitric oxide synthases (NOSs) are ubiquitous enzymes that play a pivotal role in the regulation of myocardial function in health and disease. The discovery of both a neuronal NOS (nNOS) and an endothelial NOS (eNOS) isoform in the myocardium and the availability of genetically modified mice with selective eNOS or nNOS gene deletion have been of crucial importance for understanding the role of constitutive nitric oxide (NO) production in the myocardium. eNOS and nNOS are homologou...

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Publication status:
Published

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Publisher copy:
10.1016/j.yjmcc.2011.09.006

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
Journal:
Journal of molecular and cellular cardiology
Volume:
52
Issue:
2
Pages:
341-350
Publication date:
2012-02-01
DOI:
EISSN:
1095-8584
ISSN:
0022-2828
Source identifiers:
180448
Language:
English
Keywords:
Pubs id:
pubs:180448
UUID:
uuid:6bf937ff-a26a-4ea6-a8d5-4bfb3e652244
Local pid:
pubs:180448
Deposit date:
2012-12-19

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