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Journal article

TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres

Abstract:

Background and aims: Shorter telomeres have been associated with increased risk of malignancy, including colorectal cancer (CRC). Telomere length is heritable and may be an intermediate phenotype linked to genetic susceptibility to CRC. Methods: In a large sample, the study investigated whether candidate single nucleotide polymorphisms (SNP) in 'telomere biology' genes were associated with telomere length in leucocytes. SNP associated with an increased risk of CRC were searched for separately...

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Publisher copy:
10.1136/gut.2011.239772

Authors


Journal:
Gut More from this journal
Volume:
61
Issue:
2
Pages:
248-254
Publication date:
2012-02-01
DOI:
EISSN:
1468-3288
ISSN:
0017-5749
Language:
English
Pubs id:
pubs:245932
UUID:
uuid:6be75933-e15e-49da-8220-58ae38224db6
Local pid:
pubs:245932
Source identifiers:
245932
Deposit date:
2012-12-19

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