Journal article icon

Journal article

Variants in autophagy-related genes and clinical characteristics in melanoma: a population-based study

Abstract:

Autophagy has been linked with melanoma risk and survival, but no polymorphisms in autophagy-related (ATG) genes have been investigated in relation to melanoma progression. We examined five single-nucleotide polymorphisms (SNPs) in three ATG genes (ATG5; ATG10; and ATG16L) with known or suspected impact on autophagic flux in an international population-based case-control study of melanoma. DNA from 911 melanoma patients was genotyped. An association was identified between (GG) (rs2241880) and...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1002/cam4.929

Authors


More from this funder
Grant:
PreventiveMedicine
DivisionofEpidemiology, Biostatistics
Publisher:
John Wiley & Sons Ltd Publisher's website
Journal:
Cancer Medicine Journal website
Volume:
5
Issue:
11
Pages:
3336-3345
Publication date:
2016-11-01
Acceptance date:
2016-09-07
DOI:
ISSN:
2045-7634
Language:
English
Keywords:
Pubs id:
pubs:655447
UUID:
uuid:6bdff5fa-d975-495b-a35d-3ac59be7ce95
Local pid:
pubs:655447
Source identifiers:
655447
Deposit date:
2016-12-22

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP