Journal article
Sex-differential impact of human cytomegalovirus infection on in vitro reactivity to toll-like receptor 2, 4 and 7/8 stimulation in Gambian infants
- Abstract:
-
Human cytomegalovirus (HCMV) infection rates approach 100% by the first year of life in low-income countries. It is not known if this drives changes to innate immunity in early life and thereby altered immune reactivity to infections and vaccines. Given the panoply of sex differences in immunity, it is feasible that any immunological effects of HCMV would differ in males and females. We analysed ex vivo innate cytokine responses to a panel of toll-like receptor (TLR) ligands in 108 nine-month...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Medical Research Council
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Bibliographic Details
- Publisher:
- MDPI Publisher's website
- Journal:
- Vaccines Journal website
- Volume:
- 8
- Issue:
- 3
- Article number:
- 407
- Publication date:
- 2020-07-22
- Acceptance date:
- 2020-07-20
- DOI:
- EISSN:
-
2076-393X
- Pmid:
-
32707906
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1123257
- Local pid:
- pubs:1123257
- Deposit date:
- 2020-08-31
Terms of use
- Copyright holder:
- Cox et al.
- Copyright date:
- 2020
- Rights statement:
- © 2020 by the authors. Licensee MDPI, Basel, Switzerland.
- Notes:
- This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
- Licence:
- CC Attribution (CC BY)
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