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The mechanism of cell differentiation in Bacillus subtilis.

Abstract:

Sporulation in Bacillus subtilis serves as a model for the development of two different cell types from a single cell. Although much information has been accumulated about the mechanisms that initiate the developmental programmes, important questions remain that can be answered only by quantitative analysis. Here we develop, with the help of existing and new experimental results, a mathematical model that reproduces published in vitro experiments and explains how the activation of the key tra...

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Publisher copy:
10.1038/nature04666

Authors


Journal:
Nature
Volume:
441
Issue:
7091
Pages:
371-374
Publication date:
2006-05-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:6ba42611-bf15-4c11-bfca-80407fdc1a26
Source identifiers:
246456
Local pid:
pubs:246456

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