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Cytokine blockade in rheumatoid arthritis.

Abstract:
As we enter the 2000's it is clear that cytokine blockade is an effective therapeutic strategy for rheumatoid arthritis. In this brief review, we will review the rationale for anti TNFalpha therapy, the current status of therapy and focus on the regulation of TNFalpha production in rheumatoid synovium. New approaches to studying TNF regulation in RA and of elucidating the controversial role of T cells in this complex disease will be described.
Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Bondeson, J More by this author
Foxwell, BM More by this author
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Journal:
Advances in experimental medicine and biology
Volume:
490
Pages:
119-127
Publication date:
2001
ISSN:
0065-2598
URN:
uuid:6b9acc0e-ef94-4760-b8b2-66d5488c32c0
Source identifiers:
224464
Local pid:
pubs:224464

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