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Non-functioning pituitary adenomas with positive immunoreactivity for ACTH behave more aggressively than ACTH immunonegative tumours but do not recur more frequently.

Abstract:

OBJECTIVES: Anecdotal reports have suggested that silent corticotroph tumours behave in an aggressive fashion; however, clear comparative data with other non-functioning adenomas (NFAs) are lacking. The aims of the study were, first, to review the natural history of those non-functioning pituitary adenomas with positive immunoreactivity for ACTH and secondly, to determine whether this subgroup behave more aggressively than ACTH immunonegative NFAs by means of comparison with existing departme...

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Authors


Bradley, KJ More by this author
Turner, HE More by this author
Journal:
Clinical endocrinology
Volume:
58
Issue:
1
Pages:
59-64
Publication date:
2003-01-05
DOI:
EISSN:
1365-2265
ISSN:
0300-0664
URN:
uuid:6b969251-f9d0-486c-9caa-598f4b70878d
Source identifiers:
914
Local pid:
pubs:914

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