Journal article
Bioprocess decision support tool for scalable manufacture of extracellular vesicles
- Abstract:
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Newly recognized as natural nanocarriers that deliver biological information between cells, extracellular vesicles (EVs), including exosomes and microvesicles, provide unprecedented therapeutic opportunities. Large‐scale and cost‐effective manufacturing is imperative for EV products to meet commercial and clinical demands; successful translation requires careful decisions that minimize financial and technological risks. Here, we develop a decision support tool (DST) that computes the most cos...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 3.1MB)
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- Publisher copy:
- 10.1002/bit.26809
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Authors
Funding
+ National Science Foundation
More from this funder
Grant:
Graduate Research Fellowships Program (B.E.M
+ Fonds Européen de Développement Économique et Régional
More from this funder
Grant:
COMPETE
program (J.M.K
+ Fundação para a Ciência e a Tecnologia
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Grant:
MIT-PortugalTB/ECE/0013/2013
(J.M.K
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Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- Biotechnology and Bioengineering Journal website
- Volume:
- 116
- Issue:
- 2
- Pages:
- 307-319
- Publication date:
- 2018-11-08
- Acceptance date:
- 2018-08-06
- DOI:
- EISSN:
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1097-0290
- ISSN:
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0006-3592
- Pmid:
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30063243
- Source identifiers:
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894179
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:894179
- UUID:
-
uuid:6b866490-0f2c-4bf6-bb36-ea1fc0b9b187
- Local pid:
- pubs:894179
- Deposit date:
- 2018-08-17
Terms of use
- Copyright holder:
- Wiley Periodicals, Inc
- Copyright date:
- 2018
- Notes:
-
Copyright © 2018 2018 The Authors. Biotechnology and Bioengineering Published by Wiley Periodicals, Inc.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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