- Abstract:
-
Newly recognized as natural nanocarriers that deliver biological information between cells, extracellular vesicles (EVs), including exosomes and microvesicles, provide unprecedented therapeutic opportunities. Large‐scale and cost‐effective manufacturing is imperative for EV products to meet commercial and clinical demands; successful translation requires careful decisions that minimize financial and technological risks. Here, we develop a decision support tool (DST) that computes the most cos...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 3.1MB)
-
- Publisher copy:
- 10.1002/bit.26809
-
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- Grant:
- National Science Scholarship (K.S.N.)
- Grant:
- (J.A.S. and D.A.B.)
- Grant:
- Graduate Research Fellowships Program (B.E.M)
- Publisher:
- Wiley Publisher's website
- Journal:
- Biotechnology and Bioengineering Journal website
- Volume:
- 116
- Issue:
- 2
- Pages:
- 307-319
- Publication date:
- 2018-11-08
- Acceptance date:
- 2018-08-06
- DOI:
- EISSN:
-
1097-0290
- ISSN:
-
0006-3592
- Pubs id:
-
pubs:894179
- URN:
-
uri:6b866490-0f2c-4bf6-bb36-ea1fc0b9b187
- UUID:
-
uuid:6b866490-0f2c-4bf6-bb36-ea1fc0b9b187
- Local pid:
- pubs:894179
- Language:
- English
- Keywords:
- Copyright holder:
- Wiley Periodicals, Inc.
- Copyright date:
- 2018
- Notes:
-
Copyright © 2018 2018 The Authors. Biotechnology and Bioengineering Published by Wiley Periodicals, Inc.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Journal article
Bioprocess decision support tool for scalable manufacture of extracellular vesicles
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Funding
+ Agency for Science,
Technology and Research, Singapore
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+ Oxford-UCL Center for the Advancement of Sustainable Medical Innovation
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+ National Science Foundation
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