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Journal article

Bioprocess decision support tool for scalable manufacture of extracellular vesicles

Abstract:

Newly recognized as natural nanocarriers that deliver biological information between cells, extracellular vesicles (EVs), including exosomes and microvesicles, provide unprecedented therapeutic opportunities. Large‐scale and cost‐effective manufacturing is imperative for EV products to meet commercial and clinical demands; successful translation requires careful decisions that minimize financial and technological risks. Here, we develop a decision support tool (DST) that computes the most cos...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1002/bit.26809

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Oxford college:
Kellogg
Role:
Author
ORCID:
0000-0003-2634-0268
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Grant:
Summer Scholars Program (J.A.S)
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Grant:
Graduate Research Fellowships Program (B.E.M)
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Publisher:
Wiley Publisher's website
Journal:
Biotechnology and Bioengineering Journal website
Volume:
116
Issue:
2
Pages:
307-319
Publication date:
2018-11-08
Acceptance date:
2018-08-06
DOI:
EISSN:
1097-0290
ISSN:
0006-3592
Pubs id:
pubs:894179
URN:
uri:6b866490-0f2c-4bf6-bb36-ea1fc0b9b187
UUID:
uuid:6b866490-0f2c-4bf6-bb36-ea1fc0b9b187
Local pid:
pubs:894179

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