Journal article
Increased T cell trafficking as adjunct therapy for HIV-1
- Abstract:
-
Although antiretroviral drug therapy suppresses human immunodeficiency virus-type 1 (HIV-1) to undetectable levels in the blood of treated individuals, reservoirs of replication competent HIV-1 endure. Upon cessation of antiretroviral therapy, the reservoir usually allows outgrowth of virus and approaches to targeting the reservoir have had limited success. Ongoing cycles of viral replication in regions with low drug penetration contribute to this persistence. Here, we use a mathematical mode...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Oxford Martin School
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All Souls College
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Department of Zoology, University of Oxford
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Computational Biology Journal website
- Volume:
- 14
- Issue:
- 3
- Pages:
- e1006028.
- Publication date:
- 2018-03-01
- Acceptance date:
- 2018-02-07
- DOI:
- EISSN:
-
1553-7358
- ISSN:
-
1553-734X
Item Description
- Pubs id:
-
pubs:823123
- UUID:
-
uuid:6b80b81a-635d-46bd-87c5-2803c887b246
- Local pid:
- pubs:823123
- Source identifiers:
-
823123
- Deposit date:
- 2018-02-08
Terms of use
- Copyright holder:
- Fryer et al
- Copyright date:
- 2018
- Notes:
- © 2018 Fryer et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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