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The pathogenesis of dengue

Abstract:

Dengue is an important cause of childhood and adult morbidity in Asian and Latin American countries and its geographic footprint is growing. The clinical manifestations of dengue are the expression of a constellation of host and viral factors, some acquired, others intrinsic to the individual. The virulence of the virus plus the flavivirus infection history, age, gender and genotype of the host all appear to help shape the severity of infection. Similarly, the characteristics of the innate an...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Journal:
Vaccine
Volume:
29
Issue:
42
Pages:
7221-7228
Publication date:
2011-09-23
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
Source identifiers:
179689
Language:
English
Keywords:
Pubs id:
pubs:179689
UUID:
uuid:6b6bac79-fc8e-4bed-949e-05d8c3cdd195
Local pid:
pubs:179689
Deposit date:
2012-12-19

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