- Abstract:
-
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer death. Despite improvements in the clinical management, the prognosis of PDAC remains dismal. In the present comprehensive review, we will examine the knowledge of PDAC genetics and the new insights into human genome sequencing and clonal evolution. Additionally, the biology and the role of the stroma in tumour progression and response to treatment will be presented. Furthermore, we will describe the evidence on tum...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Publisher copy:
- 10.1016/j.bbcan.2014.12.001
-
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- Publisher:
- Elsevier Publisher's website
- Journal:
- Biochimica et biophysica acta Journal website
- Volume:
- 1855
- Issue:
- 1
- Pages:
- 61-82
- Publication date:
- 2015-01-05
- DOI:
- EISSN:
-
1879-2561
- ISSN:
-
0006-3002
- URN:
-
uuid:6b6b8856-8a2d-4d5a-9851-273698fb2768
- Source identifiers:
-
492616
- Local pid:
- pubs:492616
- Copyright holder:
- Elsevier B.V.
- Copyright date:
- 2015
Journal article
Pancreatic ductal adenocarcinoma: From genetics to biology to radiobiology to oncoimmunology and all the way back to the clinic.
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Kidani Memorial Trust
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Oxford Cancer Imaging Centre
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Oxford Cancer Research Centre
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