Journal article
Pancreatic ductal adenocarcinoma: From genetics to biology to radiobiology to oncoimmunology and all the way back to the clinic.
- Abstract:
-
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer death. Despite improvements in the clinical management, the prognosis of PDAC remains dismal. In the present comprehensive review, we will examine the knowledge of PDAC genetics and the new insights into human genome sequencing and clonal evolution. Additionally, the biology and the role of the stroma in tumour progression and response to treatment will be presented. Furthermore, we will describe the evidence on tum...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1016/j.bbcan.2014.12.001
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Authors
Funding
Oxford Cancer Imaging Centre
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Oxford Cancer Research Centre
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Kidani Memorial Trust
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Biochimica et biophysica acta Journal website
- Volume:
- 1855
- Issue:
- 1
- Pages:
- 61-82
- Publication date:
- 2015-01-01
- DOI:
- EISSN:
-
1879-2561
- ISSN:
-
0006-3002
- Source identifiers:
-
492616
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:492616
- UUID:
-
uuid:6b6b8856-8a2d-4d5a-9851-273698fb2768
- Local pid:
- pubs:492616
- Deposit date:
- 2015-11-23
Terms of use
- Copyright holder:
- Elsevier BV
- Copyright date:
- 2015
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