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Simvastatin in non-insulin-dependent diabetes mellitus: effect on serum lipids, lipoproteins and haemostatic measures.

Abstract:

The clinical efficacy of the 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMGCoA) reductase inhibitor simvastatin in the treatment of hypercholesterolaemia in non-insulin-dependent diabetes (NIDDM), was examined in a double-blind placebo-controlled study of 6 months in 70 patients with NIDDM (age 25-70 years), of whom 57 were randomised to placebo (29 patients) or simvastatin for 6 months, following a 3-month run-in on diet. Patients were hypercholesterolaemic (7.8 (7.6-8.0) (mean (95% confidence ...

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Institution:
University of Oxford
Department:
Oxford
Role:
Author
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Journal:
Diabetes research and clinical practice
Volume:
23
Issue:
2
Pages:
111-119
Publication date:
1994-03-01
DOI:
EISSN:
1872-8227
ISSN:
0168-8227
Source identifiers:
72802
Language:
English
Keywords:
Pubs id:
pubs:72802
UUID:
uuid:6b66654c-e98a-4f60-a848-fa74044fad10
Local pid:
pubs:72802
Deposit date:
2012-12-19

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