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Metabolic effects associated with ICS in patients with COPD and comorbid type 2 diabetes: a historical matched cohort study

Abstract:
Background Management guidelines for chronic obstructive pulmonary disease (COPD) recommend that inhaled corticosteroids (ICS) are prescribed to patients with the most severe symptoms. However, these guidelines have not been widely implemented by physicians, leading to widespread use of ICS in patients with mild-to-moderate COPD. Of particular concern is the potential risk of worsening diabetic control associated with ICS use. Here we investigate whether ICS therapy in patie... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Target Discovery Institute
Role:
Author
ORCID:
0000-0002-3890-7201
More by this author
Role:
Author
ORCID:
0000-0001-9153-4662
Publisher:
Public Library of Science
Journal:
PLoS ONE More from this journal
Volume:
11
Issue:
9
Article number:
e0162903
Publication date:
2016-09-22
Acceptance date:
2016-08-30
DOI:
ISSN:
1932-6203
Pmid:
27658209
Language:
English
Pubs id:
pubs:648065
UUID:
uuid:6b5ea3e1-84cd-4fe9-bce2-adb39cee4c61
Local pid:
pubs:648065
Source identifiers:
648065
Deposit date:
2018-07-12

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