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Mycobacterium tuberculosis PPD-induced immune biomarkers measurable in vitro following BCG vaccination of UK adolescents by multiplex bead array and intracellular cytokine staining

Abstract:

Background: The vaccine efficacy reported following Mycobacterium bovis Bacillus Calmette Guerin (BCG) administration to UK adolescents is 77% and defining the cellular immune response in this group can inform us as to the nature of effective immunity against tuberculosis. The aim of this study was to identify which cytokines and lymphocyte populations characterise the peripheral blood cellular immune response following BCG vaccination.

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1471-2172-11-35

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Publisher:
BioMed Central
Journal:
BMC Immunology More from this journal
Volume:
11
Article number:
35
Publication date:
2010-07-07
Acceptance date:
2010-07-07
DOI:
EISSN:
1471-2172
Language:
English
Keywords:
UUID:
uuid:6b58908f-d1df-4fb5-8c39-9d2ed33be09a
Local pid:
pubs:66218
Source identifiers:
66218
Deposit date:
2012-12-19

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