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Journal article

Recurrent ETNK1 mutations in atypical chronic myeloid leukemia.

Abstract:

Despite the recent identification of recurrent SETBP1 mutations in atypical chronic myeloid leukemia (aCML), a complete description of the somatic lesions responsible for the onset of this disorder is still lacking. To find additional somatic abnormalities in aCML, we performed whole-exome sequencing on 15 aCML cases. In 2 cases (13.3%), we identified somatic missense mutations in the ETNK1 gene. Targeted resequencing on 515 hematological clonal disorders revealed the presence of ETNK1 varian...

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Publication status:
Published

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Journal:
Blood
Volume:
125
Issue:
3
Pages:
499-503
Publication date:
2015-01-05
DOI:
EISSN:
1528-0020
ISSN:
0006-4971
URN:
uuid:6b55e3bc-eea2-4f69-b1f6-23e44872e87e
Source identifiers:
488393
Local pid:
pubs:488393

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