Journal article icon

Journal article

Embracing the complexity of RNA regulatory networks: layer by layer.

Abstract:

The alternative splicing (AS) of precursor mRNA is tightly regulated and serves to generate a vast repertoire of RNA and protein variants and to enable expression in a cell-specific manner1. Furthermore, AS profoundly expands the functional capacity of the genome by impacting other regulatory layers, including mRNA transcription, turnover, transport, and translation. Equally, factors regulating chromatin and transcription complexes influence AS. This extensive crosstalk dictates the need to d...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1093/cvr/cvx085

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Oxford college:
All Souls College
Role:
Author
Publisher:
Oxford University Press Publisher's website
Journal:
Cardiovascular Research Journal website
Volume:
113
Issue:
8
Pages:
e22-e23
Publication date:
2017-06-22
DOI:
EISSN:
1755-3245
ISSN:
0008-6363
Pmid:
28863440
Source identifiers:
708815
Language:
English
Keywords:
Pubs id:
pubs:708815
UUID:
uuid:6b4d0ab4-6061-41ed-bd21-cf73974d1e9e
Local pid:
pubs:708815
Deposit date:
2017-10-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP