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Development of a robust nanoscaffold as a modular vaccine platform

Abstract:

Protein nanoparticles have been used as platforms to multimerize and present otherwise weakly immunogenic antigens to the immune system. Virus-like particles (VLPs) are self-assembling protein cages, forming the basis of safe and immunogenic vaccines that have been administered to millions of people. However, the creation of chimeric VLPs that display heterologous antigens through either genetic fusion or chemical coupling continues to be a challenge. To address this challenge, a modular v...

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Division:
MSD
Department:
Biochemistry
Role:
Author

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Role:
Supervisor
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Name:
Clarendon Fund
Funding agency for:
Bruun, T
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Name:
St. Edmund Hall
Funding agency for:
Bruun, T
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:6b407904-5ced-4c79-a061-617fb129e172
Deposit date:
2018-07-03

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