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IA-2 antibody prevalence and risk assessment of early insulin requirement in subjects presenting with type 2 diabetes (UKPDS 71).

Abstract:

AIMS/HYPOTHESIS: Established autoimmune markers of type 1 diabetes, including islet cell autoantibodies (ICA) and autoantibodies to glutamic acid decarboxylase (GADA) have been used to screen people presenting with type 2 diabetes for latent autoimmune diabetes in adults. We have examined the prevalence of autoantibodies to protein tyrosine phosphatase isoforms IA-2 (IA-2A) and IA-2beta/phogrin (IA-2betaA) in a cohort of adult UKPDS patients thought to have type 2 diabetes, and investigated t...

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Publication status:
Published

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Publisher copy:
10.1007/s00125-005-1691-9

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Journal:
Diabetologia
Volume:
48
Issue:
4
Pages:
703-708
Publication date:
2005-04-05
DOI:
EISSN:
1432-0428
ISSN:
0012-186X
URN:
uuid:6b3bf337-aa36-4642-bb7c-b8663d35fe16
Source identifiers:
24490
Local pid:
pubs:24490

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