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Journal article

Bronchial thermoplasty and biological therapy as targeted treatments for severe uncontrolled asthma

Abstract:

Although a small proportion of patients with asthma have severe disease, it accounts for the majority of morbidity related to the illness. Severe asthma comprises a heterogeneous group of phenotypes. Targeted treatments for these phenotypes represent a major advancement in the management of severe asthma. Omalizumab, a monoclonal antibody to IgE, improves asthma control in patients with a predominant allergic phenotype. Monoclonal antibodies targeted to interleukin 4α and interleukin 5 have s...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Target Discovery Institute
Role:
Author
Publisher:
Elsevier
Journal:
Lancet Respiratory Medicine More from this journal
Volume:
4
Issue:
7
Pages:
585–592
Publication date:
2016-05-24
DOI:
EISSN:
2213-2619
ISSN:
2213-2600
Language:
English
Pubs id:
pubs:625602
UUID:
uuid:6b35d817-828b-4edf-9512-b85237b66c11
Local pid:
pubs:625602
Source identifiers:
625602
Deposit date:
2016-07-06

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