- Abstract:
-
In the search for effective vaccines against intracellular pathogens such as HIV, tuberculosis and malaria, recombinant viral vectors are increasingly being used to boost previously primed T cell responses. Published data have shown prime-boost vaccination with BCG-MVA85A (modified vaccinia virus Ankara expressing antigen 85A) to be highly immunogenic in humans as measured by ex vivo IFN-gamma ELISPOT. Here, we used polychromatic flow cytometry to investigate the phenotypic and functional pro...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/eji.200737504
-
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- Journal:
- European journal of immunology
- Volume:
- 37
- Issue:
- 11
- Pages:
- 3089-3100
- Publication date:
- 2007-11-05
- DOI:
- EISSN:
-
1521-4141
- ISSN:
-
0014-2980
- URN:
-
uuid:6b2eebbd-762b-47fb-883c-1edd7b7e46bc
- Source identifiers:
-
40595
- Local pid:
- pubs:40595
- Language:
- English
- Keywords:
- Copyright date:
- 2007
Journal article
Immunisation with BCG and recombinant MVA85A induces long-lasting, polyfunctional Mycobacterium tuberculosis-specific CD4+ memory T lymphocyte populations.
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