Journal article
A kit formulated under good manufacturing practices for labeling human epidermal growth factor with 111In for radiotherapeutic applications.
- Abstract:
-
UNLABELLED: Our goal was to design and manufacture a kit under good manufacturing practices (GMP) for the preparation of (111)In-DTPA-hEGF Injection, a novel targeted radiotherapeutic agent for advanced epidermal growth factor receptor (EGFR)-positive breast cancer. METHODS: Human EGF (hEGF) was derivatized with diethylenetriaminepentaacetic acid (DTPA) and then purified by size-exclusion chromatography and ultrafiltration. Kits were prepared by dispensing 0.25 mg (1 mL) of DTPA-hEGF in 1 mo...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Journal of nuclear medicine : official publication, Society of Nuclear Medicine
- Volume:
- 45
- Issue:
- 4
- Pages:
- 701-708
- Publication date:
- 2004-04-01
- EISSN:
-
1535-5667
- ISSN:
-
0161-5505
- Source identifiers:
-
131319
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:131319
- UUID:
-
uuid:6b080890-04a5-49b0-bd6d-750e528c0f35
- Local pid:
- pubs:131319
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2004
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