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Journal article

Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data.

Abstract:

OBJECTIVE: This study examined how differences in the BMI distribution of type 2 diabetic case subjects affected genome-wide patterns of type 2 diabetes association and considered the implications for the etiological heterogeneity of type 2 diabetes. RESEARCH DESIGN AND METHODS: We reanalyzed data from the Wellcome Trust Case Control Consortium genome-wide association scan (1,924 case subjects, 2,938 control subjects: 393,453 single-nucleotide polymorphisms [SNPs]) after stratifying case subj...

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Publication status:
Published

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Publisher copy:
10.2337/db08-0906

Authors


Timpson, NJ More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Weedon, MN More by this author
Randall, J More by this author
Ouwehand, WH More by this author
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Journal:
Diabetes
Volume:
58
Issue:
2
Pages:
505-510
Publication date:
2009-02-05
DOI:
EISSN:
1939-327X
ISSN:
0012-1797
URN:
uuid:6b06d95f-e0fd-4454-95d7-d8d31b4274be
Source identifiers:
1029
Local pid:
pubs:1029

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