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MEG can map short and long-term changes in brain activity following deep brain stimulation for chronic pain.

Abstract:

Deep brain stimulation (DBS) has been shown to be clinically effective for some forms of treatment-resistant chronic pain, but the precise mechanisms of action are not well understood. Here, we present an analysis of magnetoencephalography (MEG) data from a patient with whole-body chronic pain, in order to investigate changes in neural activity induced by DBS for pain relief over both short- and long-term. This patient is one of the few cases treated using DBS of the anterior cingulate cortex...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0037993

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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
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Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
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Wellcome Trust More from this funder
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Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
7
Issue:
6
Pages:
e37993
Publication date:
2012
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
URN:
uuid:6afe97ba-5d43-4231-9973-3b8d34cfae0a
Source identifiers:
334777
Local pid:
pubs:334777

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