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Comparison of serotonin and dopamine release in substantia nigra and ventral tegmental area: region and species differences.

Abstract:

In this study, we compare the electrically evoked, somatodendritic release of dopamine (DA) with axonal release of serotonin (5-HT) in the substantia nigra (SN) and ventral tegmental area (VTA) in vitro by using fast-scan cyclic voltammetry with carbon-fibre microelectrodes. Furthermore, we have examined transmitter release in these regions in guinea-pig compared with rat. Somatodendritic DA was released, as shown previously, in guinea-pig VTA, SN pars compacta (SNc), and occasionally in SN p...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
Journal:
Journal of neurochemistry
Volume:
69
Issue:
6
Pages:
2378-2386
Publication date:
1997-12-05
DOI:
EISSN:
1471-4159
ISSN:
0022-3042
URN:
uuid:6acda0d6-96e9-41c6-82bf-63578386a73f
Source identifiers:
114294
Local pid:
pubs:114294

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