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Journal article

Molecular detection of localized prostate cancer using quantitative methylation-specific PCR on urinary cells obtained following prostate massage.

Abstract:

PURPOSE: The diagnosis of localized prostate cancer is difficult due to a lack of cancer-specific biomarkers. Many patients require repeat prostate biopsies to diagnose the disease. We investigated whether aberrant promoter hypermethylation in prostatic fluid could reliably detect prostate cancer. EXPERIMENTAL DESIGN: Urine samples were collected after prostate massage from 95 patients with localized prostate cancer undergoing radical prostatectomy (63 pT(1), 31 pT(2), and 1 pT(3)) and from ...

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Publication status:
Published

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Authors


Rouprêt, M More by this author
Hupertan, V More by this author
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Journal:
Clinical cancer research : an official journal of the American Association for Cancer Research
Volume:
13
Issue:
6
Pages:
1720-1725
Publication date:
2007-03-05
DOI:
EISSN:
1557-3265
ISSN:
1078-0432
URN:
uuid:6ac1fb1a-8276-4123-ba99-c53af6530f6c
Source identifiers:
120665
Local pid:
pubs:120665

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