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Journal article

Total synthesis of (-)-saliniketals A and B.

Abstract:: A stereocontrolled total synthesis of the orthinine decarboxylase inhibitors saliniketals A and B is described. Key features of the 17-step route include the use of two boron aldol/reduction sequences to control six of the nine stereocenters, an intramolecular Wacker-type cyclization to install the bicyclic acetal core, and a late-stage Stille coupling to append the requisite (2 Z,4 E)-dienamide.

Publication status:: Published

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APA Style

Paterson, I., Razzak, M., & Anderson, E. (2008). Total synthesis of (-)-saliniketals A and B. Organic Letters, 10(15), 3295–3298.

MLA Style

Paterson, I., et al. “Total Synthesis of (-)-Saliniketals A and B.” Organic Letters, vol. 10, no. 15, 2008, pp. 3295–98.

Chicago Style

Paterson, I, M Razzak, and E Anderson. 2008. “Total Synthesis of (-)-Saliniketals A and B.” Organic Letters 10 (15): 3295–98.
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Publisher copy:: 10.1021/ol801148d

Authors

+ Paterson, I More by this author

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Author

+ Razzak, M More by this author

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Author

+ Anderson, E More by this author

Institution:

University of Oxford

Division:

MPLS

Department:

Chemistry

Sub department:

Organic Chemistry

Role:

Author

Bibliographic Details

Journal:: Organic letters
Volume:: 10
Issue:: 15
Pages:: 3295-3298
Publication date:: 2008-08-01
DOI:: 10.1021/ol801148d
EISSN:: 1523-7052
ISSN:: 1523-7060

Item Description

Language:: English
Keywords:: Micromonosporaceae

Bicyclo Compounds, Heterocyclic

Stereoisomerism
Pubs id:: pubs:117843
UUID:: uuid:6ab76de3-9691-4a30-93ec-8a9e2709af12
Local pid:: pubs:117843
Source identifiers:: 117843
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 2008

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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