Journal article icon

Journal article

Three models for the regulation of polygenic scores in reproduction

Abstract:

The past few years have brought significant breakthroughs in understanding human genetics. This knowledge has been used to develop ‘polygenic scores’ (or ‘polygenic risk scores’) which provide probabilistic information about the development of polygenic conditions such as diabetes or schizophrenia. They are already being used in reproduction to select for embryos at lower risk of developing disease. Currently, the use of polygenic scores for embryo selection is subject to existing regulations...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1136/medethics-2020-106588

Authors


More by this author
Institution:
University of Oxford
Division:
HUMS
Department:
Philosophy Faculty
Role:
Author
More by this author
Institution:
University of Oxford
Division:
HUMS
Department:
Philosophy Faculty
Role:
Author
More from this funder
Name:
Wellcome Trust
Grant:
203132/Z/16/Z
104848/Z/14/Z
Publisher:
BMJ Publishing Group
Journal:
Journal of Medical Ethics More from this journal
Volume:
47
Issue:
12
Article number:
e91
Publication date:
2021-01-18
Acceptance date:
2020-12-06
DOI:
EISSN:
1473-4257
ISSN:
0306-6800
Language:
English
Keywords:
Pubs id:
1148125
Local pid:
pubs:1148125
Deposit date:
2020-12-08

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP