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Journal article

ChpC controls twitching motility-mediated expansion of Pseudomonas aeruginosa biofilms in response to serum albumin, mucin and oligopeptides

Abstract:

Twitching motility-mediated biofilm expansion occurs via coordinated, multi-cellular collective behaviour to allow bacteria to actively expand across surfaces. Type-IV pili (T4P) are cell-associated virulence factors which mediate twitching motility via rounds of extension, surface attachment and retraction. The Chp chemosensory system is thought to respond to environmental signals to regulate the biogenesis, assembly and twitching motility function of T4P. In other well characterised chemose...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1099/mic.0.000911

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
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Name:
Wellcome Trust
Grant:
106064/Z/14/Z
Publisher:
Microbiology Society
Journal:
Microbiology More from this journal
Volume:
166
Issue:
7
Pages:
669–678
Publication date:
2020-06-01
Acceptance date:
2020-03-18
DOI:
EISSN:
1465-2080
ISSN:
1350-0872
Pmid:
32478653
Language:
English
Keywords:
Pubs id:
1109600
Local pid:
pubs:1109600
Deposit date:
2020-06-12

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