Journal article : Review
E2F1: Cause and consequence of DNA replication stress
- Abstract:
-
In mammalian cells, cell cycle entry occurs in response to the correct stimuli and is promoted by the transcriptional activity of E2F family members. E2F proteins regulate the transcription of S phase cyclins and genes required for DNA replication, DNA repair, and apoptosis. The activity of E2F1, the archetypal and most heavily studied E2F family member, is tightly controlled by the DNA damage checkpoints to modulate cell cycle progression and initiate programmed cell death, when required. Al...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Funding
Bibliographic Details
- Publisher:
- Frontiers Media Publisher's website
- Journal:
- Frontiers in Molecular Biosciences Journal website
- Volume:
- 7
- Article number:
- 599332
- Publication date:
- 2021-02-16
- DOI:
- EISSN:
-
2296-889X
Item Description
- Language:
- English
- Keywords:
- Subtype:
- Review
- Pubs id:
-
1174195
- Local pid:
- pubs:1174195
- Deposit date:
- 2021-05-05
Terms of use
- Copyright holder:
- S Fouad et al.
- Copyright date:
- 2021
- Rights statement:
- © 2021 Fouad, Hauton and D'Angiolella. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Licence:
- CC Attribution (CC BY)
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