Journal article icon

Journal article

An open-label, randomised study of dihydroartemisinin-piperaquine versus artesunate-mefloquine for falciparum malaria in Asia.

Abstract:

BACKGROUND: The artemisinin-based combination treatment (ACT) of dihydroartemisinin (DHA) and piperaquine (PQP) is a promising novel anti-malarial drug effective against multi-drug resistant falciparum malaria. The aim of this study was to show non-inferiority of DHA/PQP vs. artesunate-mefloquine (AS+MQ) in Asia. METHODS AND FINDINGS: This was an open-label, randomised, non-inferiority, 63-day follow-up study conducted in Thailand, Laos and India. Patients aged 3 months to 65 years with Plas...

Expand abstract
Publication status:
Published

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pone.0011880

Authors


Valecha, N More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Krudsood, S More by this author
Expand authors...
Medicines for Malaria Venture More from this funder
University of Oxford More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
5
Issue:
7
Pages:
Article: e11880
Publication date:
2010
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
URN:
uuid:6a7ad5fe-ec1e-440f-a8eb-c800ef822177
Source identifiers:
67531
Local pid:
pubs:67531

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP