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Journal article

Axonal loss in multiple sclerosis: a pathological survey of the corticospinal and sensory tracts.

Abstract:

Clinical, imaging, and pathological studies in multiple sclerosis have generally emphasized the relative preservation of axons in comparison with myelin. Recent evidence, however, demonstrates that axonal loss is also significant, affects long tracts such as the corticospinal and sensory tracts and relates closely to functional disability. Accordingly, the distribution and extent of this axonal loss is the focus of the current investigation. Post-mortem material of 55 multiple sclerosis patie...

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Publication status:
Published

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Publisher copy:
10.1093/brain/awh118

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Brain : a journal of neurology
Volume:
127
Issue:
Pt 5
Pages:
1009-1018
Publication date:
2004-05-01
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
Source identifiers:
32664
Language:
English
Keywords:
Pubs id:
pubs:32664
UUID:
uuid:6a73aa59-1f24-461c-9d9e-1c9eb5595eb1
Local pid:
pubs:32664
Deposit date:
2012-12-19

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