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Journal article

Recombination in human herpesvirus-8 strains from Uganda and evolution of the K15 gene.

Abstract:

Human herpesvirus-8 (HHV-8) is believed to be the aetiological agent of Kaposi's sarcoma (KS). KS accounts for half the reported cancer cases in Uganda, and occurs in endemic and epidemic [human immunodeficiency virus (HIV)-associated] forms. We confirmed a high prevalence (74%) of HHV-8 antibodies in 114 HIV-negative Ugandan blood donors, and characterized the genomes of HHV-8 strains present in 30 adult Ugandan KS patients. Phylogenetic analysis of the uniquely variable K1 gene indicated th...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
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Journal:
Journal of general virology
Volume:
82
Issue:
Pt 10
Pages:
2393-2404
Publication date:
2001-10-01
EISSN:
1465-2099
ISSN:
0022-1317
Source identifiers:
97806
Language:
English
Keywords:
Pubs id:
pubs:97806
UUID:
uuid:6a6fa815-1745-49fd-b76d-78774a5120f2
Local pid:
pubs:97806
Deposit date:
2012-12-19

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